GastroPlus 10.1
Overview of GastroPlus 10.1 GastroPlus is a leading mechanistically based simulation software developed by Simulations Plus, Inc., designed for physiologically-based pharmacokinetics (PBPK) and physiologically-based biopharmaceutics modeling (PBBM). It enables researchers, pharmaceutical scientists, and drug developers to predict drug absorption, distribution, metabolism, excretion (ADME), and pharmacodynamics across various routes of administration (e.g., oral, intravenous, dermal, inhalation) in humans and animals. Version 10.1 is part of the established GastroPlus lineup, focusing on accurate in silico predictions to optimize drug formulation, reduce animal testing, and accelerate R&D workflows. Key Features of GastroPlus 10.1 Core Modeling Capabilities: Simulates gastrointestinal (GI) absorption using the Advanced Compartmental Absorption and Transit (ACAT™) model, which accounts for factors like dissolution, precipitation, metabolism, and transport in GI compartments....